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Featured Research | Dr. Samrat Das, Assistant Professor, Department of Life Sciences | 2026 Human Cancer Genomes Harbor the Mutational Signature of Tobacco-Specific Nitrosamines NNN and NNK New Study Identifies a Distinct Cancer-Causing Signature Left by Tobacco-Specific Chemicals in the Genome Tobacco smoke contains two potent cancer-causing chemicals, NNN and NNK, which are known to damage DNA by forming what scientists call pyridyloxobutyl adducts. Until now, however, it was not well understood exactly what genetic "fingerprint," or mutational signature, this damage leaves behind in human cancers. In this study, researchers used advanced..